Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5158237 | European Journal of Medicinal Chemistry | 2017 | 44 Pages |
Abstract
A series of novel water-soluble 4-quinolone-3-carboxamides was prepared and evaluated as antitumor agents. The representative compound 8k could trigger p53/Bax-independent colorectal cancer cell apoptosis via inducing ROS accumulation.157
Related Topics
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Authors
Zeyan Zhang, Xingpeng Xiao, Tong Su, Jinyi Wu, Jianwei Ren, Jiongchang Zhu, Xiaodong Zhang, Rihui Cao, Runlei Du,