Prodrug strategy for cancer cell-specific targeting: A recent overview

Article ID	Journal	Published Year	Pages	File Type
5158430	European Journal of Medicinal Chemistry	2017	48 Pages	PDF

Keywords

Mitomycin C IAA DCM HSA 5-FC GSH HRP GSSG N-acetyl-l-cysteine PTX MMT HIF ADCS NAC NQO1 NTR nitroreductase PABC HRPC ADEPT MMAE GDEPT TyrRS Carboxypeptidase G2 CPG2 AdV MDR 5-FU mAb DOX Mmps CPT SEC CyP MMC NIR 5-fluorocytosine NAD(P)H:quinone oxidoreductase 1 ROS Hydrogen peroxide Adenovirus human serum albumin alpha-fetoprotein Non-natural amino acid Monoclonal antibody indole-3-acetic acid Folic acid AFP Antibody-directed enzyme prodrug therapy Gene-directed enzyme prodrug therapy Doxorubicin Cancer cytochrome P450s Hypoxia-inducible factor 5-fluorouracil Near infrared Matrix metalloproteinases Multidrug resistance Nitric oxide Target therapy H2O2 Paclitaxel Horseradish peroxidase Prodrug camptothecin Antibody-drug conjugates Glutathione glutathione disulfide Reactive oxygen species

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Prodrug strategy for cancer cell-specific targeting: A recent overview

Authors

Xian Zhang, Xiang Li, Qidong You, Xiaojin Zhang,