Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective Î±1D adrenoceptor antagonists

Article ID	Journal	Published Year	Pages	File Type
5158445	European Journal of Medicinal Chemistry	2017	46 Pages	PDF

Keywords

K2CO3 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene Boc2O Xphos NaOMe mCPBA Dppf m-Chloroperoxybenzoic acid Xantphos Et3N Pd(PPh3)4 Palladium(II) acetate N-methyl-2-pyrrolidone H2SO4 NMP BH3 WSC HCl DME adrenoceptor HOBt 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 1,2-Dimethoxyethane N,N-diisopropylethylamine Pd(OAc)2 Pd/C hydrochloric acid Bladder outlet obstruction Borane BOO Tetrakis(triphenylphosphine)palladium(0)triethylamine Sulfuric acid Zinc cyanide Sodium methoxide Methoxyamine Benign prostatic hyperplasia BPH Palladium on carbon Potassium Carbonate Oxalyl chloride

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Identification of 3,4-dihydro-2H-thiochromene 1,1-dioxide derivatives with a phenoxyethylamine group as highly potent and selective Î±1D adrenoceptor antagonists

Authors

Nobuki Sakauchi, Hideki Furukawa, Junya Shirai, Ayumu Sato, Haruhiko Kuno, Reiko Saikawa, Masato Yoshida,