| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5158457 | European Journal of Medicinal Chemistry | 2017 | 38 Pages |
Abstract
A series of tacrine-like compounds 7a-u were designed and synthesized as potent AChE inhibitors with high selectivity, low toxicity on hepatocytes, neuroprotective and β-amyloid aggregation inhibitory activity.195
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease](/preview/png/5158457.png "First Page Preview: New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease")
Authors
Leili Jalili-Baleh, Hamid Nadri, Alireza Moradi, Syed Nasir Abbas Bukhari, Mojtaba Shakibaie, Mandana Jafari, Mostafa Golshani, Farshad Homayouni Moghadam, Loghman Firoozpour, Ali Asadipour, Saeed Emami, Mehdi Khoobi, Alireza Foroumadi,