| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5158459 | European Journal of Medicinal Chemistry | 2017 | 54 Pages |
Abstract
A set of forty pyrazolochalcone conjugates and explored their cytotoxic activity against a panel of sixty cancer cell lines. Fifteen conjugates of the series showed excellent growth inhibition (13b-e, 13h-j, 14c-d, 15 a, 15 c-d, 16b, 16d and 18f; GI50 for MCF-7: 0.4-20 μM). 13b, 13c, 13d, 16b and 14d were evaluated for their mechanism in human breast cancer cell line (MCF-7).340
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Authors
Anver Basha Shaik, Garikapati Koteswara Rao, G. Bharath Kumar, Nibeditha Patel, Vangala Santhosh Reddy, Irfan Khan, Sunitha Rani Routhu, C. Ganesh Kumar, Immadi Veena, Kunta Chandra Shekar, Madan Barkume, Shailesh Jadhav, Aarti Juvekar, Jyoti Kode,