Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5158484 | European Journal of Medicinal Chemistry | 2017 | 30 Pages |
Abstract
In this study, forty-four chiral triazole derivatives have been synthesized via asymmetric synthesis, and their in vitro antiviral activities against EV71 and CVB3 were fully investigated in cell-based assays, and the results indicated the most potential molecules are the compounds 10 and 43 with S-configuration, and which exhibit good TI values compared with the control Ribavirin.518
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Authors
Xiufang Cao, Wenda Wang, Shuangshuang Wang, Longzhu Bao,