Article ID Journal Published Year Pages File Type
5158484 European Journal of Medicinal Chemistry 2017 30 Pages PDF
Abstract
In this study, forty-four chiral triazole derivatives have been synthesized via asymmetric synthesis, and their in vitro antiviral activities against EV71 and CVB3 were fully investigated in cell-based assays, and the results indicated the most potential molecules are the compounds 10 and 43 with S-configuration, and which exhibit good TI values compared with the control Ribavirin.518
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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