| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5158527 | European Journal of Medicinal Chemistry | 2017 | 10 Pages |
Abstract
A series of tacrine-derived compounds were synthesized as cholinesterases inhibitors. Among them, compound 6i with 4-(3-bromophenyl) moiety showed the most potent activity against AChE/BuChE (IC50s of 0.069 and 1.35 μM, respectively).150
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![New tacrine-derived AChE/BuChE inhibitors: Synthesis and biological evaluation of 5-amino-2-phenyl-4H-pyrano[2,3-b]quinoline-3-carboxylates](/preview/png/5158527.png "First Page Preview: New tacrine-derived AChE/BuChE inhibitors: Synthesis and biological evaluation of 5-amino-2-phenyl-4H-pyrano[2,3-b]quinoline-3-carboxylates")
Authors
Mohammad Eghtedari, Yaghoub Sarrafi, Hamid Nadri, Mohammad Mahdavi, Alireza Moradi, Farshad Homayouni Moghadam, Saeed Emami, Loghman Firoozpour, Ali Asadipour, Omid Sabzevari, Alireza Foroumadi,