Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5158531 | European Journal of Medicinal Chemistry | 2017 | 6 Pages |
Abstract
A new dioxidovanadium (V) complex (1) has been synthesized and characterized. It potently and selectively inhibited protein tyrosine phosphatase 1B, increased the phosphorylation of PTP1B substrates and exhibited lower cytotoxicity than VOSO4, suggesting a promising candidate for novel vanadium-based anti-diabetic drug.240
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Authors
Yuqi Jia, Liping Lu, Miaoli Zhu, Caixia Yuan, Shu Xing, Xueqi Fu,