Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5158637 | European Journal of Medicinal Chemistry | 2017 | 50 Pages |
Abstract
Fifteen novel benzimidazole compounds were synthesized in order to investigate their inhibitory potency against hMAO-A and hMAO-B enzymes. The compound 4e displayed significant hMAO-B inhibition, notable interactions in the active site, non-cytotoxicity, non-genotoxicity and a good predicted ADME profile.192
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Authors
Ãzgür Devrim Can, Derya Osmaniye, Ãmide Demir Ãzkay, Begüm Nurpelin SaÄlık, Serkan Levent, Sinem Ilgın, Merve Baysal, Yusuf Ãzkay, Zafer Asım Kaplancıklı,