Article ID Journal Published Year Pages File Type
5158637 European Journal of Medicinal Chemistry 2017 50 Pages PDF
Abstract
Fifteen novel benzimidazole compounds were synthesized in order to investigate their inhibitory potency against hMAO-A and hMAO-B enzymes. The compound 4e displayed significant hMAO-B inhibition, notable interactions in the active site, non-cytotoxicity, non-genotoxicity and a good predicted ADME profile.192
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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