Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5158712 | European Journal of Medicinal Chemistry | 2017 | 34 Pages |
Abstract
Four cyclometalated iridium(III) complexes containing guanidinium ligands have been synthesized and characterized. These complexes display moderate cytotoxicity by specifically targeting mitochondria and inducing a cascade of apoptotic events related to mitochondrial dysfunction.311
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xing-Dong Song, Xia Kong, Shu-Fen He, Jia-Xi Chen, Jing Sun, Bing-Bing Chen, Jin-Wu Zhao, Zong-Wan Mao,