| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5158732 | European Journal of Medicinal Chemistry | 2017 | 9 Pages |
Abstract
Structural optimization produced a novel series of pyrrolopyrimidine based phenylpiperidine carboxamides as potent Akt inhibitors. Notably, 10h exhibited robust antiproliferative effects in both mantle cell lymphoma cell lines and primary patient tumor cells.180
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Authors
Yang Liu, Yanzhen Yin, Zhen Zhang, Carrie J. Li, Hui Zhang, Daoguang Zhang, Changying Jiang, Krystle Nomie, Liang Zhang, Michael L. Wang, Guisen Zhao,