| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5158889 | European Journal of Medicinal Chemistry | 2017 | 106 Pages |
Keywords
DMFPLK1BOCNLPGSK3βnek2TFAshRNASACDCMtert-butoxycarbonylHec1N-iodosuccinimideNiSN,N-dimethylformamideSmall interfering RNAshort hairpin RNAsiRNATrifluoroacetic acidSelectivityImidazo[1,2-a]pyridinespindle assembly checkpointChromosome instabilityCinRoom temperatureDIADDichloromethaneDiisopropyl azodicarboxylateAntitumor activityPolo-like kinase 1Glycogen synthase kinase-3β
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities](/preview/png/5158889.png "First Page Preview: Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities")
Authors
Jian-Bei Xi, Yan-Fen Fang, Brendan Frett, Meng-Li Zhu, Tong Zhu, Yan-Nan Kong, Feng-Jie Guan, Yun Zhao, Xiong-Wen Zhang, Hong-yu Li, Ming-Liang Ma, Wenhao Hu,