Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5158934 | European Journal of Medicinal Chemistry | 2017 | 35 Pages |
Abstract
A series of azaacridine compounds were rationally designed and synthesized as EGFR and Src dual inhibitors. The typical compound 13b could inhibit the invasion of tumor cells and induce cancer cells apoptosis in the nano-molar range.263
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhishan Cui, Shaopeng Chen, Yanwei Wang, Chunmei Gao, Yuzong Chen, Chunyan Tan, Yuyang Jiang,