Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors

A novel series of triazine-triazole derivatives were synthesized and evaluated for their α-glucosidase inhibitory activity. Among these compounds, 7i displayed the most potent α-glucosidase inhibitory activity with IC50 values of 11.63 ± 0.15 μM as compared to the standard drug acarbose (817.38 ± 6.27 μM).