Design, synthesis, and biological evaluation of cyclic-indole derivatives as anti-tumor agents via the inhibition of tubulin polymerization

Article ID	Journal	Published Year	Pages	File Type
5159049	European Journal of Medicinal Chemistry	2017	40 Pages	PDF

Keywords

HUVECS HR-MS CA-4 HMTA high resolution mass spectra Cell cycle arrest Apoptosis standard error SARS Human umbilical vein endothelial cells Vascular disrupting agents Antiproliferative activity Tubulin polymerization inhibitor Hexamethylenetetramine Propidium iodide

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Design, synthesis, and biological evaluation of cyclic-indole derivatives as anti-tumor agents via the inhibition of tubulin polymerization

Authors

Jun Yan, Jinhui Hu, Baijiao An, Li Huang, Xingshu Li,