Article ID Journal Published Year Pages File Type
5159061 European Journal of Medicinal Chemistry 2017 30 Pages PDF
Abstract
Oxo-bridged diiron(III) complexes have been explored for cancer-specific cytotoxicity. Complexes exploit cancer-specific condition of excess of H2O2 to show cancer selective anticancer activity through the generation of excess of ROS. Photodecaroxylation of the complexes further increased ROS concentration in the cancer cells leading to lethality.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , ,