| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5159087 | European Journal of Medicinal Chemistry | 2017 | 29 Pages |
Abstract
New potent isophthalic acid derivatives armed with imidazolyl and indolyl groups as β-secretase inhibitors have been synthesized. The most potent compound, 11b, displayed an EC50 value of 0.29 μM.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hamadeh Tarazi, Raed Abu Odeh, Raed Al-Qawasmeh, Imad Abu Yousef, Wolfgang Voelter, Taleb H. Al-Tel,