| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5164250 | Phytochemistry | 2015 | 15 Pages |
Abstract
Gingerols and the corresponding shogaols are the major pungent compounds present in the rhizomes of fresh and dried ginger (Zingiber officinale), respectively. The compounds have a favourable toxicity profile, but are cytotoxic towards a range of cancer cell lines. Tumours induced in several animal models were successfully treated by gingerols.
Keywords
NF-κBShogaolsSarco-endoplasmic reticulum Ca2+-ATPaseZingiber officinaleOVA12-O-tetradecanoylphorbol-13-acetateiNOSMBCMICtPAHepG2LPSTRPV1COXBSAinducible NO synthaseROSbovine serum albumincyclooxygenaseOvalbuminNutraceuticalminimum bactericidal concentrationMinimal inhibitory concentrationSarcoplasmic reticulumGingerShogaolAntidiabeticAnticancerAnti-inflammatoryNuclear factor-kappa BSERCAlipopolysaccharideNitric oxideprostaglandintransient receptor potential cation channel subfamily V member 1Reactive oxygen speciesGingerolGingerols
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ruchi Badoni Semwal, Deepak Kumar Semwal, Sandra Combrinck, Alvaro M. Viljoen,