Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5164300 | Phytochemistry | 2015 | 13 Pages |
Abstract
Aerial parts of Tragopogon tommasinii Sch.Bip. (Asteraceae, Cichorieae) yielded 21 natural compounds, including seven new stilbenoids; three simple bibenzyls, two benzylphthalides, and two glucopyranosyl-de-methoxy-canna-bispiradienoides. Structures were established by HR mass spectrometry and extensive 1D and 2D NMR spectroscopy. Bioactivity of new compounds on human neutrophils and on their release of IL-8, IL-1β TNF-α, and MMP-9 and on the surface expression of TLR-4 in particular was investigated.
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Authors
Sebastian Granica, Jakub P. Piwowarski, Antonio Randazzo, Peter Schneider, Barbara Å»yżyÅska-Granica, Christian Zidorn,