Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5164587 | Phytochemistry | 2014 | 10 Pages |
Abstract
DE-17 induced apoptosis in SEM and Jurkat cell lines. ROS induction, a decreased mRNA expression of antioxidant enzymes and intracellular GSH content were detected in treated cells. DE-17 induced mitochondrial depolarization, and caspase-3 and -9 activation. Daucane esters induces apoptotic cell death through a ROS-mediated mechanism in human leukemia cells.75
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Authors
Stefano Dall'Acqua, Maria Antonella Linardi, Roberta Bortolozzi, Maria Clauser, Sara Marzocchini, Filippo Maggi, Marcello Nicoletti, Gabbriella Innocenti, Giuseppe Basso, Giampietro Viola,