Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro

Article ID	Journal	Published Year	Pages	File Type
5164745	Phytochemistry	2014	9 Pages	PDF

Abstract

Fresh leaf concentrate of Moringa oleifera (MC) utilized in situ for bioconversion of glucosinolates (1-4) to chemically stable isothiocyanates (5-8). MC significantly reduced inflammatory biomarkers in macrophages.146

Keywords

TNFα Nfr2 ITCs IL-1β iNOS Moringa oleifera NF-κB IL-6 keap1 Chronic inflammation Isothiocyanates interleukin-6 Interleukin-1 beta Trolox Equivalents tumor necrosis factor alpha inducible nitric oxide synthase Sulforaphane antioxidant response elements nuclear factor (erythroid-derived 2)-like 2 nuclear factor kappa-light-chain-enhancer of activated B cells Moringaceae Nitric oxide ARE Kelch-like ECH-associated protein 1 Glucosinolates

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro

Authors

Carrie Waterman, Diana M. Cheng, Patricio Rojas-Silva, Alexander Poulev, Julia Dreifus, Mary Ann Lila, Ilya Raskin,