Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5164982 | Phytochemistry | 2014 | 11 Pages |
Abstract
- Eighteen saponins never reported before have been isolated from S. asteriscus.
- Their structures have been elucidated by 1D and 2D-NMR experiments as well as ESIMS analysis.
- The aglycones of compounds 8-18 are highly hydroxylated oleanane-type triterpenes, never reported in literature.
- The cytotoxic activity of the isolated compounds has been evaluated against three cancer cell lines.
- Compounds 1, 5 and 17 displayed weak activity with IC50 values ranging from 50 to 75 μM.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Milena Masullo, Lalita Calabria, Dario Gallotta, Cosimo Pizza, Sonia Piacente,