Article ID Journal Published Year Pages File Type
5165264 Phytochemistry 2013 6 Pages PDF
Abstract
► The aerial parts of Goniothalamus australis were chemically investigated. ► Two pyridocoumarin alkaloids were isolated along with 8 known natural products. ► A biogenetic pathway for goniothalines A and B is proposed. ► All compounds were tested for antimalarial activity using Plasmodium falciparum (3D7). ► Sauristolactam and (−)-anonaine displayed IC50 values of 9 and 7 μM, respectively.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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