Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5165309 | Phytochemistry | 2012 | 7 Pages |
Abstract
⺠The inhibition kinetics of cholinesterases by β-carbolinium salts were determined. ⺠A molecular modeling study of its enzyme-ligand interactions was carried out. ⺠The positive charge does not mimic the natural substrate. ⺠Selectivity was observed between enzymes of up to 20 times for the salts.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Juliana M. Torres, Aline F. Lira, Daniel R. Silva, Lucas M. Guzzo, Carlos M.R. Sant'Anna, Arthur E. Kümmerle, Victor M. Rumjanek,