Comparative metabolite profiling and fingerprinting of medicinal licorice roots using a multiplex approach of GC-MS, LC-MS and 1D NMR techniques

Article ID	Journal	Published Year	Pages	File Type
5165410	Phytochemistry	2012	13 Pages	PDF

Abstract

âº Four Glycyrrhiza species (Glycyrrhiza glabra, uralensis, inflata, echinata) were profiled. âº NMR profiles allow quantification and Î±- vs. Î²-glycyrrhizin differentiation. âº LC/MS is superior to NMR for species classification. âº New chemotaxonomic markers are suggested for Glycyrrhiza species.

Keywords

Glycyrrhiza glabra L.ESI Licochalcone A PDA MSN HCA nuclear magnetic resonance GC–MS LC–MS PCA Principal component analysis Photodiode array detection NMR hierarchical clustering, Hierarchical cluster analysis Licorice Mass spectrometry Tandem mass spectrometry Anticancer activity NMR-based metabolomics Liquorice liquid chromatography Gas chromatography Glycyrrhizin electrospray ionization