| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165416 | Phytochemistry | 2012 | 11 Pages |
Abstract
⺠Hypericum perforatum and the 4 compound mixture inhibited inflammatory mediators in macrophages. ⺠The 4 compounds required SOCS3 activation to inhibit the inflammatory response. ⺠H. perforatum ethanol extract had SOCS3 independent anti-inflammatory activity. ⺠The 4 compounds inhibited LPS-induced cytokines without activating SOCS3.
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Authors
Nan Huang, Ludmila Rizshsky, Catherine C. Hauck, Basil J. Nikolau, Patricia A. Murphy, Diane F. Birt,