| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165441 | Phytochemistry | 2012 | 13 Pages |
Abstract
⺠Abietane diterpenes preferentially inhibit topoisomerase I. ⺠A new binding mode is described. ⺠Cell cycle is influenced in the G1/G0 or the S-phase. ⺠Induction of DNA damage is observed in the comet assay.
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Chemistry
Organic Chemistry
Authors
Marcio Fronza, Evelyn Lamy, Stefan Günther, Berta Heinzmann, Stefan Laufer, Irmgard Merfort,