| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165501 | Phytochemistry | 2012 | 9 Pages |
Abstract
⺠EtOAc extract of the stem bark of M. sessilifolia was active against P. falciparum. ⺠A monomeric acyl indole and four bisindoles alkaloids were isolated. ⺠NMR experiments were performed at low temperature for bisindoles linked at C-3/C-10. ⺠Compound 2 displayed potent antiplasmodial activity (4.4 μM, S.I = 48). ⺠Tabernaelegantine B and D were active against MRC-5 and L6 cells.
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Authors
Marion Girardot, Christiane Deregnaucourt, Alexandre Deville, Lionel Dubost, Roger Joyeau, Lucile Allorge, Philippe Rasoanaivo, Lengo Mambu,