| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165549 | Phytochemistry | 2011 | 10 Pages |
Abstract
⺠Piperine and its analogue phenylamide are toxic to Leishmania amazonensis parasites. ⺠They cause alterations on parasite mitochondrial structure and function. ⺠The parasite's cell cycle and neutral lipid composition is affected by these compounds. ⺠Isobologram showed a synergism between these compounds on leishmanicidal effect. ⺠The use of both compounds together leads to a synergism on leishmanicdal effect.
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Authors
C. Ferreira, D.C. Soares, C.B. Barreto-Junior, M.T. Nascimento, L. Freire-de-Lima, J.C. Delorenzi, M.E.F. Lima, G.C. Atella, E. Folly, T.M.U. Carvalho, E.M. Saraiva, L.H. Pinto-da-Silva,