Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5165597 | Phytochemistry | 2012 | 12 Pages |
Abstract
⺠We performed structural characterization of 16 limonoids, including 5 natural compounds. ⺠A SPR-based screening was performed, demonstrating that kotschyin D interacts with Hsp90. ⺠Kotschyin D inhibits Hsp90 via an ATP-independent mechanism, binding its middle domain.
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Authors
Fabrizio Dal Piaz, Nicola Malafronte, Adriana Romano, Dario Gallotta, Maria Antonietta Belisario, Giuseppe Bifulco, Maria Josefine Gualtieri, Rokia Sanogo, Nunziatina De Tommasi, Claudio Pisano,