| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165645 | Phytochemistry | 2011 | 7 Pages |
Abstract
⺠Three isolectins (KSA-1-3) were isolated from the cultivated Kappaphycus striatum. ⺠KSAs are monomeric proteins of about 28 kDa having identical N-terminal sequences. ⺠KSAs have affinity for high-mannose-linked glycoproteins but not for monosaccharides. ⺠KSA-2 shows the strict binding-specificity for high mannose N-glycans. ⺠KSAs are evaluated with a unique carbohydrate probe, promising their medicinal uses.
Keywords
SDSMVLKSAOAACV-NESATFAN-acetyl-d-glucosamineGlcNAcESI-MSCarbohydrate-binding specificitySVNGRFTTrifluoroacetic acidYieldN-terminal amino acid sequenceMolecular massRed algasodium dodecyl sulfateLectinMannoseManhuman immunodeficiency virusHIVPurificationpyridylaminatedhigh performance liquid chromatographyHPLC
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Le Dinh Hung, Yuichiro Sato, Kanji Hori,