| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165698 | Phytochemistry | 2011 | 7 Pages |
Abstract
⺠Six bufadienolides were obtained by biotransformation using cell suspension cultures of Saussurea involucrata. ⺠A Î1-reduction was observed for the first time in the biotransformation of bufadienolides. ⺠The compounds showed potent cytotoxic activities against human hepatoma (HepG2) and breast cancer (MCF-7) cell lines with IC50 values of 0.05-0.50 μM.
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Authors
Xing Zhang, Min Ye, Yin-hui Dong, Hong-bo Hu, Si-jia Tao, Jun Yin, De-an Guo,