| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165780 | Phytochemistry | 2010 | 10 Pages |
Abstract
This report describes the first systematic structure-activity relationship study of cytokinin anticancer activity against a diverse panel of human cancer cell lines. Analysis of the activity of the most effective cytokinin, ortho-topolin riboside, against NCI60 cell panel suggests that its mechanism of action differs from that of the standard antineoplastics. The synthesis of new cytokinin nucleotides is also described.
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
JiÅà Voller, Marek Zatloukal, René Lenobel, Karel Doležal, Tibor BéreÅ¡, VladimÃr KryÅ¡tof, LukáÅ¡ SpÃchal, Percy Niemann, Petr Džubák, Marián Hajdúch, Miroslav Strnad,