Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5165836 | Phytochemistry | 2011 | 7 Pages |
Abstract
⺠Synthesis of (±)-licarin, its resolution and antiparasitary activity. ⺠(±)-Licarin A was resolved by chiral HPLC furnishing its (â) and (+) enantiomers. ⺠Schistosomicidal and trypanocidal activities were studied in vitro. ⺠For Shistosoma mansoni (±)-licarin was the most active. ⺠For Trypanosoma cruzi (â)-licarin was the most active.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
A.C. Pereira, L.G. Magalhães, U.O. Gonçalves, P.P. Luz, A.C.G. Moraes, V. Rodrigues, P.M. da Matta Guedes, A.A. da Silva Filho, W.R. Cunha, J.K. Bastos, N.P.D. Nanayakkara, M.L.A. e Silva,