| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165839 | Phytochemistry | 2011 | 10 Pages |
Abstract
⺠We investigated the constituents of the bark of Endiandra kingiana. ⺠Activity-guided isolation led to the discovery of 14 polyketides as racemic mixtures. ⺠The compounds possess an unprecedented pentacyclic framework. ⺠Seven coupled of enantiomers were obtained after chiral separations. ⺠Six compounds exhibited significant binding affinity for the antiapoptotic protein Bcl-xL.
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Authors
Aurélie Leverrier, Khalijah Awang, Françoise Guéritte, Marc Litaudon,