Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5165889 | Phytochemistry | 2010 | 6 Pages |
Abstract
This paper reports isolation of sesquiterpene lactones (SL), luteolin, apigenin, and ethyl caffeate. The investigation of the SL in vitro cytotoxicity demonstrated that glaucolide 2 and hirsutinolide 4 were toxic to HeLa cells. Compounds 1/3 and 4 were also genotoxic in an in vitro comet assay.
Related Topics
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Chemistry
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Authors
Humberto Buskuhl, Fabio L. de Oliveira, Luise Z. Blind, Rilton A. de Freitas, Andersson Barison, Francinete R. Campos, Yuri E. Corilo, Marcos N. Eberlin, Giovanni F. Caramori, Maique W. Biavatti,