| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5165919 | Phytochemistry | 2010 | 11 Pages |
Abstract
Phytochemical investigation of Symphonia globulifera (Clusiaceae) led to the isolation of nine polycyclic polyprenylated acylphloroglucinol compounds and two oxidized derivatives together with 7-epi-garcinol and 7-epi-isogarcinol. In vitro antiplasmodial assays revealed potent antimalarial activity for eleven of them. A LC/ESI-MSn study performed on polyprenylated benzophenones isolated previously provided a reliable method for their detection in the extract and structural elucidation.
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Authors
Guillaume Marti, Véronique Eparvier, Christian Moretti, Soizic Prado, Philippe Grellier, Nathalie Hue, Odile Thoison, Bernard Delpech, Françoise Guéritte, Marc Litaudon,