Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5166045 | Phytochemistry | 2009 | 7 Pages |
Abstract
An investigation of the constituents in heartwood and resin of Prunus avium is reported. A mini-library of structurally diverse flavanones and flavones was screened for human cytochrome P450 1A1, 3A4 and 19 (aromatase) inhibition and for antifungal activity against a panel of pathogenic fungi. The defensive role of these natural plant flavonoids as antifungal phytoalexins and phytoanticipins is discussed.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
James McNulty, Jerald J. Nair, Endreddy Bollareddy, Kunal Keskar, Amol Thorat, Denis J. Crankshaw, Alison C. Holloway, Ghaznia Khan, Gerard D. Wright, Linda Ejim,