| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5166048 | Phytochemistry | 2009 | 6 Pages |
Abstract
Cyclodepsipeptides, tiglicamides A-C, were isolated from a marine cyanobacterium. They inhibited a mammalian elastase in vitro (IC50 2.14-7.28 μM). These compounds are analogues of co-produced largamides A-C and their simultaneous isolation suggests that a biosynthetic enzyme with unusually relaxed substrate specificity may be operating in this cyanobacterium.
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Authors
Susan Matthew, Valerie J. Paul, Hendrik Luesch,