| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5166093 | Phytochemistry | 2010 | 5 Pages |
Abstract
TLR4 dimerization is one of the initial steps triggering the activation of TLR4. Therefore, TLR4 dimerization by isoliquiritigenin was established by co-immunoprecipitation, using IL-3 dependent Ba/F3 cells stably transfected with murine Flag- and GFP-tagged TLR4. isoliquiritigenin inhibited LPS-induced TLR4 dimerization.
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Authors
Se-Jeong Park, Hyung-Sun Youn,