Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5166096 | Phytochemistry | 2010 | 9 Pages |
Abstract
Anti-inflammatory assay-guided separation of extracts from the roots of Caesalpinia mimosoides Lamk. led to isolation of seven compounds: four diterpenes (1-4), a dimer (9), and two dibenzo[b,d]furans (10, 11) together with eleven known compounds. Compound 4 exhibited potent inhibitory activity against LPS-induced NO production and TNF-α release in RAW264.7 cell lines with IC50 values of 3.0 and 6.5 μM, respectively.
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Authors
Orapun Yodsaoue, Chatchanok Karalai, Chanita Ponglimanont, Supinya Tewtrakul, Suchada Chantrapromma,