| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5166319 | Phytochemistry | 2009 | 11 Pages |
Abstract
The evolutionary origin of Ã-lactam biosynthesis genes has been the subject of discussion for many years, and two main hypotheses have been proposed: (i) horizontal gene transfer (HGT) from bacteria to fungi or (ii) vertical decent. Recently obtained data reviewed here, strongly support the model of a combination of interkingdom HGT and recruitment of a biosynthesis gene and its cis-acting sites upon gene duplication.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Axel A. Brakhage, Marcel Thön, Petra Spröte, Daniel H. Scharf, Qusai Al-Abdallah, Sandra M. Wolke, Peter Hortschansky,