Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5166590 | Phytochemistry | 2008 | 6 Pages |
Abstract
Eight phloroglucinols, tomoeones A-H were isolated from the leaves of Hypericum ascyron. Their structures were established based on spectroscopic analyses. Cytotoxicities of tomoeones (A-H) against human tumor cell lines were evaluated. Tomoeone F (6) demonstrated significant cytotoxicity against KB cells with an IC50 value of 6.2 μg/mL.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Waka Hashida, Naonobu Tanaka, Yoshiki Kashiwada, Michiko Sekiya, Yasumasa Ikeshiro, Yoshihisa Takaishi,