Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5167097 | Phytochemistry | 2008 | 9 Pages |
Abstract
Demonstration of antifungal and antioxidant effects supports the traditional use of pipsissewa in treating skin ailments. Chemical-genetic profiling with a library of yeast deletion mutants indicated that the principal antifungal constituent, chimaphilin, had a complex mode of action, affecting a protein-protein interaction network including 26% of the genes in the profile.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Imelda J. Galván, Nadereh Mir-Rashed, Matthew Jessulat, Monica Atanya, Ashkan Golshani, Tony Durst, Philippe Petit, Virginie Treyvaud Amiguet, Teun Boekhout, Richard Summerbell, Isabel Cruz, John T. Arnason, Myron L. Smith,