Article ID Journal Published Year Pages File Type
5167122 Phytochemistry 2007 9 Pages PDF
Abstract
The extracts prepared from the stem barks of several Mexican copalchis (Hintonia latiflora, Exostema caribaeum and a commercial mixture of Hintonia standleyana and E. caribaeum) showed significant (p < 0.05) antihyperglycemic effects. From H. latiflora, the cucurbitacin 1, and several other known compounds, were isolated. Oral administration of H. latiflora extract [100 mg/kg] and 5 (30 mg/kg) to STZ-diabetic rats over a 30 day duration restored normal blood glucose levels. It was also demonstrated that the extract of H. latiflora regulated hepatic glycogen and plasma insulin levels.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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