| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5167141 | Phytochemistry | 2007 | 11 Pages |
Abstract
The active compounds, 3-hydroxyphloretin and catechol, were isolated from the Formosan apple. The compounds exhibited hydroxyl radical-scavenging activity and reduced cellular tyrosinase activity in HEMn cells. Catechol showed downregulation of the levels of tyrosinase-related proteins and mRNA. The two compounds also exhibited metal-coordinating interactions with copper ions, in a virtual model of molecular docking.
Related Topics
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Authors
Yi-Pei Lin, Feng-Lin Hsu, Chien-Shu Chen, Ji-Wang Chern, Mei-Hsien Lee,