| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5167253 | Phytochemistry | 2008 | 5 Pages |
Abstract
Bioassay-guided fractionation of Struthiola argentea (Thymelaeaceae) led to the isolation of three anthelmintic flavones 1-3, including the flavone 5,6,2â²,5â²,6â²-pentamethoxy-3â²,4â²-methylenedioxyflavone (3). The flavone 3 exhibited the most potent in vitro activity against Haemonchus contortus with 90% inhibition of larval motility (EC90) at 3.1 μg/mL.
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Authors
Sloan Ayers, Deborah L. Zink, Kenneth Mohn, Joanne S. Powell, Christine M. Brown, Terry Murphy, Robert Brand, Seef Pretorius, Dennis Stevenson, Donald Thompson, Sheo B. Singh,