| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5167461 | Phytochemistry | 2006 | 9 Pages |
Abstract
Twelve components were isolated from Spatholobus suberectus by using bio-guided assay. Among them, butin (7) is the most active component in reducing expression of cellular tyrosinase and in lowering melanin content in human epidermal melanocytes (HEMn). This inhibition is exerted through inhibition of transcription of the genes encoding tyrosinase, tyrosinase-related proteins 1 and 2.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Mei-Hsien Lee, Yi-Pei Lin, Feng-Lin Hsu, Gui-Rong Zhan, Kun-Ying Yen,