| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5167697 | Phytochemistry | 2007 | 7 Pages |
Abstract
ent-Abietane diterpenoids, hebeiabinins A-F (1-5), together with seven known diterpenoids were isolated from leaves of Isodon rubescens var. rubescens. Structures of 1-5 were established on the basis of spectroscopic analyses, including application of 2D NMR spectroscopic techniques. The diterpenoids isolated were evaluated for the cytotoxicity against A549, HT-29, and K562 tumor cell lines. Compound 5 was the most active with IC50 value of 0.91 μM against A549 cells.
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Authors
Sheng-Xiong Huang, Jian-Xin Pu, Wei-Lie Xiao, Li-Mei Li, Zhi-Ying Weng, Yan Zhou, Quan-Bin Han, Shu-Lin Peng, Li-Sheng Ding, Li-Guang Lou, Han-Dong Sun,