Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5167728 | Phytochemistry | 2006 | 9 Pages |
Abstract
The biotransformation of ent-18-acetoxy-6-ketomanoyl oxides, epimers at C-13, with Fusarium moniliforme and Neurospora crassa, are described. The main biohydroxylation have been introduced in both epimers at C-1 (ent-β) or C-11 (ent-α). In addition, with the 13-epi substrate N. crassa originated other minor hydroxylations by the ent-α face at C-1 or at C-12, whereas ent-11β-hydroxy or 11-oxo derivatives were achieved with the 13-normal substrate.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hanae Ghoumari, Mohamed-Hassan Benajiba, Andrés GarcÃa-Granados, Antonia Fernández, Antonio MartÃnez, Francisco Rivas, José M. Arias,